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Peptide record

TPDB17300

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB17300
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
WRRLRRLLRRLRRL
Physicochemical Analysis
C89H163N39O15
ANDCEQGHIKMFPSTYV
R
2019.53
13.25
8
0
6
+8
1.83
-1.279
139.29
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
272.34
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C89H163N39O15
2019.53
13.25
+8
1.83
-1.279
Evidence Records 1 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 256 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii | Front Microbiol | 2021