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Peptide record

TPDB17291

Antibacterial Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB17291
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia AFP-GFuse CAFPdb
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
FFGAIAKLAMKFLPAIYKQIQKKRK
Physicochemical Analysis
C142H232N36O29S1
NDCEHSTWV
K
2939.69
11.22
7
0
14
+7
1.08
0.016
94.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
50.69
3
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
2
Q
1
G
0
H
3
I
2
L
6
K
1
M
3
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 1 H: 0 I: 3 L: 2 K: 6 M: 1 F: 3 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
25
C142H232N36O29S1
2939.69
11.22
+7
1.08
0.016
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.8-1.6 µM

Target

Escherichia coli ATCC 35218

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 35218 (MIC 0.8-1.6 uM), P. aeruginosa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

M. smegmatis

Source & Reference

dbAMP

Other

Active against E. coli ATCC 35218 (MIC 0.8-1.6 uM), P. aeruginosa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25
Evidence 3 Activity

Activity

MIC
Antibacterial
1.6 µM

Target

Staphylococcus aureus ATCC33592 MRSA

Source & Reference

dbAMP

Other

TCC 35218 (MIC 0.8-1.6 uM), P. aeruginosa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25 uM). In addtion, oral application of Ch
Evidence 4 Activity

Activity

MIC
Antibacterial
50 µM

Target

A. flavus

Source & Reference

dbAMP

Other

sa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25 uM). In addtion, oral application of Checacin1 caused death of
Evidence 5 Activity

Activity

MIC
Antibacterial
6.25 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25 uM). In addtion, oral application of Checacin1 caused death of the testing insect pea Aphids.
Evidence 6 Activity

Activity

MIC
Antifungal
0.8-1.6 µM

Target

Escherichia coli ATCC 35218

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 35218 (MIC 0.8-1.6 uM), P. aeruginosa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (
Evidence 7 Activity

Activity

MIC
Antifungal
25 µM

Target

M. smegmatis

Source & Reference

dbAMP CAFPdb

Other

Active against E. coli ATCC 35218 (MIC 0.8-1.6 uM), P. aeruginosa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25
Evidence 8 Activity

Activity

MIC
Antifungal
1.6 µM

Target

Staphylococcus aureus ATCC33592 MRSA

Source & Reference

dbAMP CAFPdb

Other

TCC 35218 (MIC 0.8-1.6 uM), P. aeruginosa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25 uM). In addtion, oral application of Ch
Evidence 9 Activity

Activity

MIC
Antifungal
50 µM

Target

A. flavus

Source & Reference

dbAMP CAFPdb

Other

sa ATCC27853 (MIC 12.5), M. smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25 uM). In addtion, oral application of Checacin1 caused death of
Evidence 10 Activity

Activity

MIC
Antifungal
6.25 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb

Other

smegmatis (MIC 25 uM), S. aureus ATCC33592 MRSA (MIC 1.6 uM), A. flavus (MIC 50 uM), and C. albicans (MIC 6.25 uM). In addtion, oral application of Checacin1 caused death of the testing insect pea Aphids.
Evidence 11 Activity

Activity

<5% Cytotoxicity
Toxicity
12.5-25 µM
Cytotoxic
<5% Cytotoxicity | 12.5-25 | µM | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion Chelifer cancroides. | Toxins (Basel) | 2022