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Peptide record

TPDB17289

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB17289
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
GVVDIIKGAGKKFAKGLAGKIANKK
Physicochemical Analysis
C115H203N33O29
RCEQHMPSTWY
K
2512.08
10.92
7
1
11
+6
5.47
-0.024
101.60
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
4
A
0
R
1
N
1
D
0
C
0
E
0
Q
5
G
0
H
3
I
1
L
7
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 3 L: 1 K: 7 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
25
C115H203N33O29
2512.08
10.92
+6
5.47
-0.024
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ab initio Designed Antimicrobial Peptides Against Gram-Negative Bacteria | Front Microbiol | 2021