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Peptide record

TPDB17283

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB17283
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FLLKIVALLKKKLL
Physicochemical Analysis
C83H150N18O15
RNDCEQGHMPSTWY
L
1640.22
11.00
4
0
10
+4
-0.94
1.464
222.86
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
6
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 6 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C83H150N18O15
1640.22
11.00
+4
-0.94
1.464
Evidence Records 1 records
Evidence 1 Activity

Activity

40% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
40% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ab initio Designed Antimicrobial Peptides Against Gram-Negative Bacteria | Front Microbiol | 2021