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Peptide record

TPDB17250

Antibacterial Anticancer Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB17250
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
WNWTKRF
Physicochemical Analysis
C51H68N14O10
ADCEQGHILMPSYV
W
1037.19
11.49
2
0
3
+2
-2.47
-1.657
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
1060.56
2
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
7
C51H68N14O10
1037.19
11.49
+2
-2.47
-1.657
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
>128 µg/mL
Cytotoxic
IC50 | >128 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Mutasynthetic Production and Antimicrobial Characterization of Darobactin Analogs. | Microbiol Spectr | 2021
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Microbiol Spectr. 2021 Dec 22 9(3):e0153521.