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Peptide record

TPDB17225

Antibacterial Anticancer Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB17225
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
VDKPPYLPRPRPIRRPGGR
Physicochemical Analysis
C100H167N35O23
ANCEQHMFSTW
P
2227.65
12.23
6
1
4
+5
7.25
-1.532
56.32
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
66.89
1
Residue Composition
number
0
A
5
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
1
I
1
L
1
K
0
M
0
F
6
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 6 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
19
C100H167N35O23
2227.65
12.23
+5
7.25
-1.532
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
10% Hemolysis | 128 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Preparation, Characterization and Pharmacokinetic Study of N-Terminal PEGylated D-Form Antimicrobial Peptide OM19r-8. | J Pharm Sci | 2020
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
512 µM
Hemolytic Cytotoxic
0% Hemolysis | 512 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design and Characterization of a Novel Hybrid Antimicrobial Peptide OM19R Based on Oncocin and MDAP-2. | Int J Pept Res Ther | 2019