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Peptide record

TPDB17127

R23LP (TAT + AF) Antibacterial Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB17127
R23LP (TAT + AF)
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
dbAMP CPPsite3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from dbAMP and CPPsite3.0, with an available 3D structural model.
Chemical: GGGG as a Linker
Sequence
RKKRRQRRRGGGGITDFGIFIGL
Physicochemical Analysis
C115H198N44O28
ANCEHMPSWYV
RG
2645.12
12.71
8
1
6
+7
5.10
-0.957
67.83
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
6
R
0
N
1
D
0
C
0
E
1
Q
6
G
0
H
3
I
1
L
2
K
0
M
2
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 6 H: 0 I: 3 L: 1 K: 2 M: 0 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C115H198N44O28
2645.12
12.71
+7
5.10
-0.957
Free
GGGG as a Linker
L
Linear
Free
N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bt474 Cells S. Aureus, Mrsa, And B. Cereus

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Amyloidogenic fragment (AF) at C terminal
In vitro
CCCGGGCCCCSHHHHTTSCCCCGGGGCCCCC
Additional Detail Fields 1 fields
CCCGGGCCCCSHHHHTTSCCCCGGGGCCCCC