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Peptide record

TPDB17066

Bmkn-22 Antibacterial Anticancer standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB17066
Bmkn-22
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
dbAMP Peptipedia CancerPPD 2.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from dbAMP, Peptipedia, and CancerPPD 2.0, with an available 3D structural model.
Sequence
FIGAIARLLSK
Physicochemical Analysis
C56H97N15O13
NDCEQHMPTWYV
AIL
1188.48
11.49
2
0
7
+2
-1.27
1.218
160.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
1
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 1 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C56H97N15O13
1188.48
11.49
+2
-1.27
1.218
Free
L
Linear
Free
Antimicrobial
Derivative of Bmkn-2
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
inhibited biofilm formation of P. aeruginosa weakly. Dose-dependent (200-800 uM) inhibited biofilm formation and disrupted biofilms.
Evidence 2 Activity

Activity

IC50 between 29-97 µg/ml
Anticancer

Target

Tongue Squamous Cell Carcinoma
HSC-4
Tongue

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.