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Peptide record

TPDB17041

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB17041
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FIKAIARLLSKIF
Physicochemical Analysis
C75H126N18O15
NDCEQGHMPTWYV
I
1519.94
11.64
3
0
9
+3
-1.73
1.323
165.38
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
2
L
2
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 2 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C75H126N18O15
1519.94
11.64
+3
-1.73
1.323
Evidence Records 1 records
Evidence 1 Activity

Activity

69% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
69% Hemolysis | 25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Fine-Tuning of Alkaline Residues on the Hydrophilic Face Provides a Non-toxic Cationic α-Helical Antimicrobial Peptide Against Antibiotic-Resistant ESKAPE Pathogens. | Front Microbiol | 2021