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Peptide record

TPDB17038

Antibacterial Toxicity modified_plain modified
9 amino acids
Basic Information
3D PDB MODEL
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TPDB17038
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
modified_plain
Yes
A 9-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
FLKLLKKXL
Physicochemical Analysis
C51H91N11O9
ARNDCEQGHIMPSTWYV
L
1002.35
10.84
3
0
5
+3
-0.40
0.700
173.33
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
3
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C51H91N11O9
1002.35
10.84
+3
-0.40
0.700
Evidence Records 2 records
Evidence 1 Activity

Activity

18% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 64 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by α-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria. | Biomolecules | 2021
Evidence 2 Activity

Activity

43% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
43% Hemolysis | 128 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by α-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria. | Biomolecules | 2021