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Peptide record

TPDB17028

Antibacterial Anticancer Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB17028
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
KKMMKKGGKFGTFMAIGGIR
Physicochemical Analysis
C98H168N28O22S3
NDCEQHLPSWYV
GK
2186.77
11.85
6
0
8
+6
2.21
-0.230
44.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
2
I
0
L
5
K
3
M
2
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 2 L: 0 K: 5 M: 3 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C98H168N28O22S3
2186.77
11.85
+6
2.21
-0.230
Evidence Records 6 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria. | Int J Mol Sci | 2021
Evidence 2 Activity

Activity

9% Cytotoxicity
Toxicity
256 µg/mL
Cytotoxic
9% Cytotoxicity | 256 | µg/mL | target cell: Mouse leukocytes

Target

Mouse leukocytes

Source & Reference

NA
DBAASP
A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria. | Int J Mol Sci | 2021
Evidence 3 Activity

Activity

20% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria. | Int J Mol Sci | 2021
Evidence 4 Activity

Activity

9% Cytotoxicity
Toxicity
256 µg/mL
Cytotoxic
9% Cytotoxicity | 256 | µg/mL | target cell: Human leukocytes

Target

Human leukocytes

Source & Reference

NA
DBAASP
A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria. | Int J Mol Sci | 2021
Evidence 5 Activity

Activity

22% Killing
Toxicity
256 µg/mL
Cytotoxic
22% Killing | 256 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria. | Int J Mol Sci | 2021
Evidence 6 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Int J Mol Sci. 2021 Jul 31 22(15):8244.