Peptide record

TPDB17011

Antibacterial standard
37 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB17011
Antibacterial
Anti-infective peptides
dbAMP Peptipedia
standard
No
A 37-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
KVGRHLVKGLGKIFRAGKVIFCNTCKTCNGLCDYCCA
Physicochemical Analysis
C174H288N52O45S6
EQMPSW
C
4020.88
9.24
8
1
13
+6
2.86
0.278
81.62
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1865
46.38
11
Residue Composition
number
2
A
2
R
2
N
1
D
6
C
0
E
0
Q
5
G
1
H
2
I
3
L
5
K
0
M
2
F
0
P
0
S
2
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 2 N: 2 D: 1 C: 6 E: 0 Q: 0 G: 5 H: 1 I: 2 L: 3 K: 5 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 1 V: 3
Chemical Descriptors
37
C174H288N52O45S6
4020.88
9.24
+6
2.86
0.278
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antibacterial
7.6 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli ATCC 25922 (IC50 7.6 uM). Warning: Other bacteria not tested due to limited material. Reg. 12/2021