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Peptide record

TPDB17009

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB17009
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
LPRRNRWSKIWKKVTTVFS
Physicochemical Analysis
C112H180N34O25
ADCEQGHMY
RK
2402.87
12.71
6
0
7
+6
1.25
-0.821
71.58
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
11000
457.79
5
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
3
K
0
M
1
F
1
P
2
S
2
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 3 M: 0 F: 1 P: 1 S: 2 T: 2 W: 2 Y: 0 V: 2
Chemical Descriptors
19
C112H180N34O25
2402.87
12.71
+6
1.25
-0.821
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
>1200 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | >1200 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Molecular Basis of Selectivity and Activity for the Antimicrobial Peptide Lynronne-1 Informs Rational Design of Peptide with Improved Activity. | Chembiochem | 2021