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Peptide record

TPDB16932

Antibacterial Anticancer Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB16932
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
RRLIRTDTGPIIYDYFKDQLLKKGMVILRESMKNLKGM
Physicochemical Analysis
C203H343N57O54S3
ACHW
LK
4542.49
10.53
9
4
16
+5
8.12
-0.432
100.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
2980
65.60
7
Residue Composition
number
0
A
4
R
1
N
3
D
0
C
1
E
1
Q
3
G
0
H
4
I
5
L
5
K
3
M
1
F
1
P
1
S
2
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 3 C: 0 E: 1 Q: 1 G: 3 H: 0 I: 4 L: 5 K: 5 M: 3 F: 1 P: 1 S: 1 T: 2 W: 0 Y: 2 V: 1
Chemical Descriptors
38
C203H343N57O54S3
4542.49
10.53
+5
8.12
-0.432
Evidence Records 4 records
Evidence 1 Activity

Activity

12.5% Cytotoxicity
Toxicity
400 µg/mL
Cytotoxic
12.5% Cytotoxicity | 400 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Octopromycin: Antibacterial and antibiofilm functions of a novel peptide derived from Octopus minor against multidrug-resistant Acinetobacter baumannii. | Fish Shellfish Immunol | 2021
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 300 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Octopromycin: Antibacterial and antibiofilm functions of a novel peptide derived from Octopus minor against multidrug-resistant Acinetobacter baumannii. | Fish Shellfish Immunol | 2021
Evidence 3 Activity

Activity

0% Killing
Toxicity
0.25 µg/mL
Cytotoxic
0% Killing | 0.25 | µg/mL | target cell: Zebrafish embryos

Target

Zebrafish embryos

Source & Reference

NA
DBAASP
Octopromycin: Antibacterial and antibiofilm functions of a novel peptide derived from Octopus minor against multidrug-resistant Acinetobacter baumannii. | Fish Shellfish Immunol | 2021
Evidence 4 Activity

Activity

100% Killing
Toxicity
8 µg/mL
Cytotoxic
100% Killing | 8 | µg/mL | target cell: Zebrafish embryos

Target

Zebrafish embryos

Source & Reference

NA
DBAASP
Octopromycin: Antibacterial and antibiofilm functions of a novel peptide derived from Octopus minor against multidrug-resistant Acinetobacter baumannii. | Fish Shellfish Immunol | 2021