Back to search

Peptide record

TPDB16924

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB16924
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
GLWKRWKKFW
Physicochemical Analysis
C74H103N19O11
ANDCEQHIMPSTYV
KW
1434.75
11.73
4
0
5
+4
-3.45
-1.270
39.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
1150.02
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
3
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
10
C74H103N19O11
1434.75
11.73
+4
-3.45
-1.270
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
83.63 µM
Hemolytic Cytotoxic
10% Hemolysis | 83.63 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice. | J Med Chem | 2021
Evidence 2 Activity

Activity

IC50
Toxicity
38.97 µM
Cytotoxic
IC50 | 38.97 | µM | target cell: Human glomerular mesangial cells (GMC)

Target

Human glomerular mesangial cells (GMC)

Source & Reference

NA
DBAASP
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice. | J Med Chem | 2021