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Peptide record

TPDB16916

Antibacterial Hemolysis Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB16916
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia PD_Hemolysis
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GWWKRWKTWW
Physicochemical Analysis
C79H98N20O12
ANDCEQHILMFPSYV
W
1519.77
11.64
3
0
5
+3
-6.31
-1.790
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
27500
1809.48
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
1
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 5 Y: 0 V: 0
Chemical Descriptors
10
C79H98N20O12
1519.77
11.64
+3
-6.31
-1.790
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
40.79 µM
Hemolytic Cytotoxic
10% Hemolysis | 40.79 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice. | J Med Chem | 2021
Evidence 2 Activity

Activity

IC50
Toxicity
49.49 µM
Cytotoxic
IC50 | 49.49 | µM | target cell: Human glomerular mesangial cells (GMC)

Target

Human glomerular mesangial cells (GMC)

Source & Reference

NA
DBAASP
Novel Broad-Spectrum Antimicrobial Peptide Derived from Anoplin and Its Activity on Bacterial Pneumonia in Mice. | J Med Chem | 2021
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis