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Peptide record

TPDB16875

Anti-inflammatory Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB16875
Anti-inflammatory Antibacterial Toxicity
Anti-infective peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia dbAMP
standard
No
A 11-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, and Toxicity) peptide sequence curated from Peptipedia and dbAMP, with an available 3D structural model.
Sequence
FKFLARTGKFL
Physicochemical Analysis
C66H102N16O13
NDCEQHIMPSWYV
F
1327.64
11.64
3
0
6
+3
-1.74
0.400
80.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
2
K
0
M
3
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 2 M: 0 F: 3 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C66H102N16O13
1327.64
11.64
+3
-1.74
0.400
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against foodborne bacteria Gram+ S. aureus ATCC25923 (MIC 32 ug/ml), L. monocytogenes KCTC3710 (MIC 32 ug/ml), B. subtilis KCTC 2217 (MIC 5.3 ug/ml), Gram- E
Evidence 2 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

L. monocytogenes KCTC3710

Source & Reference

dbAMP

Other

Active against foodborne bacteria Gram+ S. aureus ATCC25923 (MIC 32 ug/ml), L. monocytogenes KCTC3710 (MIC 32 ug/ml), B. subtilis KCTC 2217 (MIC 5.3 ug/ml), Gram- E. coli ATCC25922, S. typhimurium KCTC1926
Evidence 3 Activity

Activity

MIC
Antibacterial
5.3 µg/mL

Target

B. subtilis KCTC 2217

Source & Reference

dbAMP

Other

teria Gram+ S. aureus ATCC25923 (MIC 32 ug/ml), L. monocytogenes KCTC3710 (MIC 32 ug/ml), B. subtilis KCTC 2217 (MIC 5.3 ug/ml), Gram- E. coli ATCC25922, S. typhimurium KCTC1926 (MIC 64 ug/ml), P. aeruginosa ATCC 2785
Evidence 4 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. typhimurium KCTC1926

Source & Reference

dbAMP

Other

KCTC3710 (MIC 32 ug/ml), B. subtilis KCTC 2217 (MIC 5.3 ug/ml), Gram- E. coli ATCC25922, S. typhimurium KCTC1926 (MIC 64 ug/ml), P. aeruginosa ATCC 27853 (MIC 5.3 ug/ml), and A. baumannii KCTC 2508 (MIC 5.3 ug/ml). Th
Evidence 5 Activity

Activity

MIC
Antibacterial
5.3 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP

Other

TC 2217 (MIC 5.3 ug/ml), Gram- E. coli ATCC25922, S. typhimurium KCTC1926 (MIC 64 ug/ml), P. aeruginosa ATCC 27853 (MIC 5.3 ug/ml), and A. baumannii KCTC 2508 (MIC 5.3 ug/ml). These MIC values are the same as those obtai
Evidence 6 Activity

Activity

MIC
Antibacterial
5.3 µg/mL

Target

A. baumannii KCTC 2508

Source & Reference

dbAMP

Other

22, S. typhimurium KCTC1926 (MIC 64 ug/ml), P. aeruginosa ATCC 27853 (MIC 5.3 ug/ml), and A. baumannii KCTC 2508 (MIC 5.3 ug/ml). These MIC values are the same as those obtained using purified PN5. I Antibiofilm:bacter
Evidence 7 Activity

Activity

5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 200 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
A Novel Antimicrobial Peptides From Pine Needles of Pinus densiflora Sieb. et Zucc. Against Foodborne Bacteria | Front Microbiol | 2021
Evidence 8 Activity

Activity

19% Cytotoxicity
Toxicity
200 µg/mL
Cytotoxic
19% Cytotoxicity | 200 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
A Novel Antimicrobial Peptides From Pine Needles of Pinus densiflora Sieb. et Zucc. Against Foodborne Bacteria | Front Microbiol | 2021