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Peptide record

TPDB16859

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB16859
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Sequence
GLLKFIKRLL
Physicochemical Analysis
C59H105N15O11
ANDCEQHMPSTWYV
L
1200.58
11.64
3
0
6
+3
-0.88
0.980
195.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
4
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 4 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C59H105N15O11
1200.58
11.64
+3
-0.88
0.980
Evidence Records 5 records
Evidence 1 Activity

Activity

15% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
15% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel anoplin-based (lipo)-peptide models show potent antimicrobial activity. | J Pept Sci | 2021
Evidence 2 Activity

Activity

37% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
37% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel anoplin-based (lipo)-peptide models show potent antimicrobial activity. | J Pept Sci | 2021
Evidence 3 Activity

Activity

37% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
37% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel anoplin-based (lipo)-peptide models show potent antimicrobial activity. | J Pept Sci | 2021
Evidence 4 Activity

Activity

52% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
52% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel anoplin-based (lipo)-peptide models show potent antimicrobial activity. | J Pept Sci | 2021
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
175.2 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 175.2 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel anoplin-based (lipo)-peptide models show potent antimicrobial activity. | J Pept Sci | 2021