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Peptide record

TPDB16850

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB16850
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
GILGKLWEGVKSIL
Physicochemical Analysis
C72H121N17O18
ARNDCQHMFPTY
GL
1512.86
9.88
2
1
7
+1
0.08
0.743
160.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
363.55
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
3
G
0
H
2
I
3
L
2
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 2 L: 3 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
14
C72H121N17O18
1512.86
9.88
+1
0.08
0.743
Evidence Records 3 records
Evidence 1 Activity

Activity

21.3% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
21.3% Hemolysis | 25 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Comparative Antimicrobial Activity of Hp404 Peptide and Its Analogs against Acinetobacter baumannii. | Int J Mol Sci | 2021
Evidence 2 Activity

Activity

45.8% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
45.8% Hemolysis | 50 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Comparative Antimicrobial Activity of Hp404 Peptide and Its Analogs against Acinetobacter baumannii. | Int J Mol Sci | 2021
Evidence 3 Activity

Activity

37.6% Killing
Toxicity
50 µM
Cytotoxic
37.6% Killing | 50 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Comparative Antimicrobial Activity of Hp404 Peptide and Its Analogs against Acinetobacter baumannii. | Int J Mol Sci | 2021