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Peptide record

TPDB16837

Antibacterial Anticancer Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB16837
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
LKKVLKAAAKAALNAVLVGANA
Physicochemical Analysis
C97H176N28O25
RDCEQHIMFPSTWY
A
2134.64
11.00
4
0
15
+4
1.42
0.873
146.82
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
8
A
0
R
2
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 8 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C97H176N28O25
2134.64
11.00
+4
1.42
0.873
Evidence Records 2 records
Evidence 1 Activity

Activity

35.4±6.28% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
35.4±6.28% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evaluating the effect of dermaseptin S4 and its derivatives on multidrug-resistant bacterial strains and on the colon cancer cell line SW620. | Environ Sci Pollut Res Int | 2021
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
6.28 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 35.4±6.28% Hemolysis=256 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Environ Sci Pollut Res Int. 2021 Aug 28(30):40908-40916.