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Peptide record

TPDB16835

Antibacterial Anticancer Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB16835
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
ALWMTLLKKVLKAAAKAALNAV
Physicochemical Analysis
C109H190N28O25S1
RDCEQGHIFPSY
A
2324.94
11.00
4
0
16
+4
-1.41
0.964
146.82
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
236.57
2
Residue Composition
number
7
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
4
K
1
M
0
F
0
P
0
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 4 M: 1 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
22
C109H190N28O25S1
2324.94
11.00
+4
-1.41
0.964
Evidence Records 2 records
Evidence 1 Activity

Activity

80±1.12% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
80±1.12% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evaluating the effect of dermaseptin S4 and its derivatives on multidrug-resistant bacterial strains and on the colon cancer cell line SW620. | Environ Sci Pollut Res Int | 2021
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
1.12 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 80±1.12% Hemolysis=256 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Environ Sci Pollut Res Int. 2021 Aug 28(30):40908-40916.