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Peptide record

TPDB16812

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB16812
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
GVIIKTLKGAAKTV
Physicochemical Analysis
C64H119N17O17
RNDCEQHMFPSWY
K
1398.75
10.84
3
0
7
+3
1.89
0.779
139.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
1
L
3
K
0
M
0
F
0
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 1 K: 3 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
14
C64H119N17O17
1398.75
10.84
+3
1.89
0.779
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
10834 µM
Hemolytic Cytotoxic
50% Hemolysis | 10834 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Study on the Structure-Activity Relationship of an Antimicrobial Peptide, Brevinin-2GUb, from the Skin Secretion of Hylarana guentheri. | Antibiotics (Basel) | 2021
Evidence 2 Activity

Activity

IC50
Toxicity
485.3 µM
Cytotoxic
IC50 | 485.3 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Study on the Structure-Activity Relationship of an Antimicrobial Peptide, Brevinin-2GUb, from the Skin Secretion of Hylarana guentheri. | Antibiotics (Basel) | 2021