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Peptide record

TPDB16811

Antibacterial Antifungal Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB16811
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
GVIIKTL
Physicochemical Analysis
C35H66N8O9
ARNDCEQHMFPSWY
I
742.96
10.10
1
0
4
+1
0.03
1.714
208.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C35H66N8O9
742.96
10.10
+1
0.03
1.714
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
11008 µM
Hemolytic Cytotoxic
50% Hemolysis | 11008 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Study on the Structure-Activity Relationship of an Antimicrobial Peptide, Brevinin-2GUb, from the Skin Secretion of Hylarana guentheri. | Antibiotics (Basel) | 2021
Evidence 2 Activity

Activity

IC50
Toxicity
346.8 µM
Cytotoxic
IC50 | 346.8 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Study on the Structure-Activity Relationship of an Antimicrobial Peptide, Brevinin-2GUb, from the Skin Secretion of Hylarana guentheri. | Antibiotics (Basel) | 2021