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Peptide record

TPDB16589

Antibacterial Hemolysis Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB16589
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia Hemolytic2
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and Hemolytic2, with an available 3D structural model.
Sequence
RIRIRIWRIRIRICTKSIPPIC
Physicochemical Analysis
C124H220N42O25S2
ANDEQGHLMFYV
I
2763.50
12.40
7
0
9
+7
2.21
0.205
141.82
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5625
203.55
4
Residue Composition
number
0
A
6
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
8
I
0
L
1
K
0
M
0
F
2
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 8 L: 0 K: 1 M: 0 F: 0 P: 2 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
22
C124H220N42O25S2
2763.50
12.40
+7
2.21
0.205
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2-4 µM

Target

Escherichia coli ATCC 25922 or UB1005 or K88 or K99 strains

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram- E. coli ATCC 25922 or UB1005 or K88 or K99 strains (MIC 2-4 uM), S. pullorum 7913 (MIC 2 uM), S. enterica serovar Typhimurium C7731 or 14208 (MIC 4 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
2 µM

Target

S. pullorum 7913

Source & Reference

dbAMP

Other

active against Gram- E. coli ATCC 25922 or UB1005 or K88 or K99 strains (MIC 2-4 uM), S. pullorum 7913 (MIC 2 uM), S. enterica serovar Typhimurium C7731 or 14208 (MIC 4 uM), P. aeruginosa 27853 (MIC 4 uM
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µM

Target

S. enterica serovar Typhimurium C7731 or 14208

Source & Reference

dbAMP

Other

oli ATCC 25922 or UB1005 or K88 or K99 strains (MIC 2-4 uM), S. pullorum 7913 (MIC 2 uM), S. enterica serovar Typhimurium C7731 or 14208 (MIC 4 uM), P. aeruginosa 27853 (MIC 4 uM), S. choleraesuis CVCC503 (MIC 4 uM), S. aureus ATCC 29213
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µM

Target

Pseudomonas aeruginosa 27853

Source & Reference

dbAMP

Other

, S. pullorum 7913 (MIC 2 uM), S. enterica serovar Typhimurium C7731 or 14208 (MIC 4 uM), P. aeruginosa 27853 (MIC 4 uM), S. choleraesuis CVCC503 (MIC 4 uM), S. aureus ATCC 29213 or 29523 or MRSA 43300 (MIC 16-
Evidence 5 Activity

Activity

MIC
Antibacterial
4 µM

Target

S. choleraesuis CVCC503

Source & Reference

dbAMP

Other

. enterica serovar Typhimurium C7731 or 14208 (MIC 4 uM), P. aeruginosa 27853 (MIC 4 uM), S. choleraesuis CVCC503 (MIC 4 uM), S. aureus ATCC 29213 or 29523 or MRSA 43300 (MIC 16-32 uM), S. epidermidis 12228 (MIC 8
Evidence 6 Activity

Activity

MIC
Antibacterial
16-32 µM

Target

Staphylococcus aureus ATCC 29213 or 29523 or MRSA 43300

Source & Reference

dbAMP

Other

or 14208 (MIC 4 uM), P. aeruginosa 27853 (MIC 4 uM), S. choleraesuis CVCC503 (MIC 4 uM), S. aureus ATCC 29213 or 29523 or MRSA 43300 (MIC 16-32 uM), S. epidermidis 12228 (MIC 8 uM), and E. faecalis 29212 (MIC 16 uM).
Evidence 7 Activity

Activity

MIC
Antibacterial
8 µM

Target

Staphylococcus epidermidis 12228

Source & Reference

dbAMP

Other

leraesuis CVCC503 (MIC 4 uM), S. aureus ATCC 29213 or 29523 or MRSA 43300 (MIC 16-32 uM), S. epidermidis 12228 (MIC 8 uM), and E. faecalis 29212 (MIC 16 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
16 µM

Target

Enterococcus faecalis 29212

Source & Reference

dbAMP

Other

us ATCC 29213 or 29523 or MRSA 43300 (MIC 16-32 uM), S. epidermidis 12228 (MIC 8 uM), and E. faecalis 29212 (MIC 16 uM).