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Peptide record

TPDB16569

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB16569
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
FRRWWWRRF
Physicochemical Analysis
C75H98N24O10
ANDCEQGHILKMPSTYV
R
1495.76
12.88
4
0
5
+4
-4.57
-1.678
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
16500
1103.12
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
9
C75H98N24O10
1495.76
12.88
+4
-4.57
-1.678
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

45% Killing
Toxicity
128 µM
Cytotoxic
45% Killing | 128 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance. | Biochem Pharmacol | 2021