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Peptide record

TPDB16560

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB16560
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
IWRWWWRWI
Physicochemical Analysis
C79H98N20O10
ANDCEQGHLKMFPSTYV
W
1487.78
12.40
2
0
7
+2
-8.25
-0.500
86.67
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
27500
1848.40
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
9
C79H98N20O10
1487.78
12.40
+2
-8.25
-0.500
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
100% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

25% Killing
Toxicity
128 µM
Cytotoxic
25% Killing | 128 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance. | Biochem Pharmacol | 2021