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Peptide record

TPDB16554

Antibacterial Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB16554
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
IRWWWRI
Physicochemical Analysis
C57H78N16O8
ANDCEQGHLKMFPSTYV
W
1115.35
12.40
2
0
5
+2
-4.55
-0.386
111.43
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
16500
1479.36
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
7
C57H78N16O8
1115.35
12.40
+2
-4.55
-0.386
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

20% Killing
Toxicity
128 µM
Cytotoxic
20% Killing | 128 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Antimicrobial peptides with symmetric structures against multidrug-resistant bacteria while alleviating antimicrobial resistance. | Biochem Pharmacol | 2021