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Peptide record

TPDB16543

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB16543
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
WRFWRFWRFWRFWRF
Physicochemical Analysis
C130H157N35O16
ANDCEQGHILKMPSTYV
RFW
2465.90
13.00
5
0
10
+5
-10.85
-0.867
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
27500
1115.21
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
5
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 5 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
15
C130H157N35O16
2465.90
13.00
+5
-10.85
-0.867
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
10% Hemolysis | 64 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria. | ACS Infect Dis | 2021
Evidence 2 Activity

Activity

50% Cell death
Toxicity
32 µM
Cytotoxic
50% Cell death | 32 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria. | ACS Infect Dis | 2021