Back to search

Peptide record

TPDB16542

Antibacterial Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB16542
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
WRFWRFWRFWRF
Physicochemical Analysis
C104H126N28O13
ANDCEQGHILKMPSTYV
RFW
1976.32
12.88
4
0
8
+4
-8.68
-0.867
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
1113.18
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
4
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 4 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
12
C104H126N28O13
1976.32
12.88
+4
-8.68
-0.867
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
10% Hemolysis | 32 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria. | ACS Infect Dis | 2021
Evidence 2 Activity

Activity

50% Cell death
Toxicity
32 µM
Cytotoxic
50% Cell death | 32 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria. | ACS Infect Dis | 2021
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis