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Peptide record

TPDB16538

Antibacterial Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB16538
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
WRLWRLWRLWRL
Physicochemical Analysis
C92H134N28O13
ANDCEQGHIKMFPSTYV
RLW
1840.26
12.88
4
0
8
+4
-6.40
-0.533
130.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
1195.49
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
12
C92H134N28O13
1840.26
12.88
+4
-6.40
-0.533
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
10% Hemolysis | 32 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria. | ACS Infect Dis | 2021
Evidence 2 Activity

Activity

50% Cell death
Toxicity
32 µM
Cytotoxic
50% Cell death | 32 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria. | ACS Infect Dis | 2021
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis