Back to search

Peptide record

TPDB16511

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB16511
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb PD_Hemolysis
standard
No
A 13-aa standard-residue multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from dbAMP, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FLQGIWDTVGKWL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C77H111N17O18
ARNCEHMPSY
GLW
1562.83
6.75
1
1
7
-0
-0.46
0.377
112.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
7.04
2
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
1
Q
2
G
0
H
1
I
2
L
1
K
0
M
1
F
0
P
0
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 2 K: 1 M: 0 F: 1 P: 0 S: 0 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
13 reviewed residue count
C77H111N17O18 sequence-only estimate (linear, free termini)
1562.83 sequence-only estimate (linear, free termini)
6.75 sequence-only estimate (linear, free termini)
-0 sequence-only estimate (linear, free termini)
-0.46 sequence-only estimate (linear, free termini)
0.377 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
37.9±0.4 µM
Hemolytic Cytotoxic
50% Hemolysis | 37.9±0.4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus. | Peptides | 2021
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis