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Peptide record

TPDB16481

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB16481
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
RIKTVTSFDLPALRWLKL
Physicochemical Analysis
C102H169N27O24
NCEQGHMY
L
2157.63
11.47
4
1
9
+3
0.06
0.194
130.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
254.91
3
Residue Composition
number
1
A
2
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
2
K
0
M
1
F
1
P
1
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 2 M: 0 F: 1 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
18
C102H169N27O24
2157.63
11.47
+3
0.06
0.194
Evidence Records 2 records
Evidence 1 Activity

Activity

24% Cytotoxicity
Toxicity
640 µg/mL
Cytotoxic
24% Cytotoxicity | 640 | µg/mL | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Combating Escherichia coli O157:H7 with Functionalized Chickpea-Derived Antimicrobial Peptides. | Adv Sci (Weinh) | 2022
Evidence 2 Activity

Activity

22% Cytotoxicity
Toxicity
640 µg/mL
Cytotoxic
22% Cytotoxicity | 640 | µg/mL | target cell: Human hepatocyte cells HL-7702 (L02)

Target

Human hepatocyte cells HL-7702 (L02)

Source & Reference

NA
DBAASP
Combating Escherichia coli O157:H7 with Functionalized Chickpea-Derived Antimicrobial Peptides. | Adv Sci (Weinh) | 2022