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Peptide record

TPDB16364

Antibacterial standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB16364
Antibacterial
Anti-infective peptides
dbAMP Peptipedia
standard
No
A 65-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
MTVTDPRSPLTTWIFFCSKKTTPPLKGAVVMPNSGLSRHLHYLRLSSRCLSNSRNTPTSSGAMIA
Physicochemical Analysis
C311H507N91O90S5
EQ
S
7121.30
11.37
10
1
22
+7
5.52
-0.174
72.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7115
99.91
24
Residue Composition
number
3
A
5
R
3
N
1
D
2
C
0
E
0
Q
3
G
2
H
2
I
7
L
3
K
3
M
2
F
6
P
10
S
8
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 5 N: 3 D: 1 C: 2 E: 0 Q: 0 G: 3 H: 2 I: 2 L: 7 K: 3 M: 3 F: 2 P: 6 S: 10 T: 8 W: 1 Y: 1 V: 3
Chemical Descriptors
65
C311H507N91O90S5
7121.30
11.37
+7
5.52
-0.174
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9.2 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
) and Salmonella 557D (18.6 mm). The recombinant peptide (BMP32r) is active against Gram- E. coli ATCC 25922 (MIC 9.2 ug/ml), C. sakazakii ATCC 29544 (MIC 18.4 ug/ml), Salmonella SH11G0461 (MIC 27.6 ug/ml), C. saka
Evidence 2 Activity

Activity

MIC
Antibacterial
18.4 µg/mL

Target

C. sakazakii ATCC 29544

Source & Reference

dbAMP

Other

recombinant peptide (BMP32r) is active against Gram- E. coli ATCC 25922 (MIC 9.2 ug/ml), C. sakazakii ATCC 29544 (MIC 18.4 ug/ml), Salmonella SH11G0461 (MIC 27.6 ug/ml), C. sakazakii (MIC 18.4-27.6 ug/ml), Gram+ E. faec
Evidence 3 Activity

Activity

MIC
Antibacterial
18.4-27.6 µg/mL

Target

C. sakazakii

Source & Reference

dbAMP

Other

ug/ml), C. sakazakii ATCC 29544 (MIC 18.4 ug/ml), Salmonella SH11G0461 (MIC 27.6 ug/ml), C. sakazakii (MIC 18.4-27.6 ug/ml), Gram+ E. faecalis ATCC 29212 (MIC 18.4 ug/ml), S. aureus ATCC 25923 (MIC 18.4-36.8 ug/ml
Evidence 4 Activity

Activity

MIC
Antibacterial
18.4 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP

Other

ug/ml), Salmonella SH11G0461 (MIC 27.6 ug/ml), C. sakazakii (MIC 18.4-27.6 ug/ml), Gram+ E. faecalis ATCC 29212 (MIC 18.4 ug/ml), S. aureus ATCC 25923 (MIC 18.4-36.8 ug/ml) inclusing antibiotic-resistant strains.
Evidence 5 Activity

Activity

MIC
Antibacterial
18.4-36.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

g/ml), C. sakazakii (MIC 18.4-27.6 ug/ml), Gram+ E. faecalis ATCC 29212 (MIC 18.4 ug/ml), S. aureus ATCC 25923 (MIC 18.4-36.8 ug/ml) inclusing antibiotic-resistant strains.