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Peptide record

TPDB16359

Antibacterial standard
61 amino acids
Basic Information
3D PDB MODEL
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TPDB16359
Antibacterial
Anti-infective peptides
dbAMP Peptipedia
standard
No
A 61-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
MDKPNIAEMIIQYEKNKDMTDTQFAFESHLSVERVHNLKSGDYEPTADEIKTVQEYIKLHQ
Physicochemical Analysis
C316H493N83O103S3
CW
E
7199.07
4.77
10
12
22
-5
26.06
-0.877
70.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
4470
62.09
17
Residue Composition
number
3
A
1
R
3
N
5
D
0
C
7
E
4
Q
1
G
3
H
5
I
3
L
6
K
3
M
2
F
2
P
3
S
4
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 3 R: 1 N: 3 D: 5 C: 0 E: 7 Q: 4 G: 1 H: 3 I: 5 L: 3 K: 6 M: 3 F: 2 P: 2 S: 3 T: 4 W: 0 Y: 3 V: 3
Chemical Descriptors
61
C316H493N83O103S3
7199.07
4.77
-5
26.06
-0.877
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Diffusion zone assay: active against Gram+ S. aureus ATCC 29213, 25923 (20.8-9 mm), E. faecalis ATCC 29212 (16 mm), L. monocytogenes CMCC 54004 (19.1 mm), Gram- E. coli ATCC 25922 (19.1 mm), Salmonella CMCC 50071 (22.7 mm), C. sakazakii ATCC 29544 (19.3 mm), also active against antibiotic-resistant C. sakazakii (17.8-20.5 mm) and Salmonella 557D (17.7 mm). Additional bacteria were tested: B. cereus ATCC 14579 (33.8 mm), S. enterica serovartyphimurium LT2 (PMID: 32749036). Reg. 11/2021 i