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Peptide record

TPDB16358

Antibacterial standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB16358
Antibacterial
Anti-infective peptides
dbAMP Peptipedia
standard
No
A 43-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
MRYKVTLDTKQQLFTVFDKKNTRVSACGKSIEEAMNKLLKMSA
Physicochemical Analysis
C216H364N60O64S4
HPW
K
4953.87
10.27
9
4
17
+5
11.03
-0.458
72.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
30.08
13
Residue Composition
number
3
A
2
R
2
N
2
D
1
C
2
E
2
Q
1
G
0
H
1
I
4
L
7
K
3
M
2
F
0
P
3
S
4
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 2 D: 2 C: 1 E: 2 Q: 2 G: 1 H: 0 I: 1 L: 4 K: 7 M: 3 F: 2 P: 0 S: 3 T: 4 W: 0 Y: 1 V: 3
Chemical Descriptors
43
C216H364N60O64S4
4953.87
10.27
+5
11.03
-0.458
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Diffusion zone assay: active against Gram+ S. aureus ATCC 29213, 25923 (19.9-20.0 mm), E.faecalis ATCC 29212 (0 mm), L. monocytogenes CMCC 54004 (17.5 mm), resistant S. aureus 1-5 (13-17.5 mm), Gram- E. coli ATCC 25922 (14.4 mm), Salmonella CMCC 50071 (14.6 mm), C. sakazakii ATCC 29544 (10.8 mm), also active against antibiotic0resistant C. sakazakii (9.4-10.9 mm) and Salmonella 557D (9.6 mm).R eg. 11/2021