TPDB

3D PDB MODEL

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TPDB ID TPDB16317

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 162-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

CQLEGDLVQSAHHLLRDLGADFPEHCLPYNANISFPSSAFPAATANHPQCHKSLWVVHESLREAGLVFQDNDIPVGEGGVTWNDQKLEDFQNLQYRLVEEGSCLSSVNGSGVLSSYFSNVTAVLQEQDSAACGWMALRRDLLWVLKSALQKHRTCFTWRGVH

FASTA

>TPDB16317|Antibacterial|length=162
CQLEGDLVQSAHHLLRDLGADFPEHCLPYNANISFPSSAFPAATANHPQCHKSLWVVHESLREAGLVFQDNDIPVGEGGVTWNDQKLEDFQNLQYRLVEEGSCLSSVNGSGVLSSYFSNVTAVLQEQDSAACGWMALRRDLLWVLKSALQKHRTCFTWRGVH

Formula C798H1214N226O240S7

Absent Amino Acids

Common Amino Acids L

Mass 18038.21

PI 5.45

Basic Residues 19

Acidic Residues 18

Hydrophobic Residues 64

Net Charge -7

Boman Index 26.41

Hydrophobicity -0.229

Aliphatic Index 84.26

Half Life

Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 32345

Absorbance 280nm 179.31

Polar Residues 47

number

13

A

7

R

8

N

9

D

6

C

9

E

10

Q

11

G

8

H

2

I

20

L

4

K

1

M

7

F

6

P

15

S

5

T

5

W

3

Y

13

V

Amino Acid Distribution

A: 13 R: 7 N: 8 D: 9 C: 6 E: 9 Q: 10 G: 11 H: 8 I: 2 L: 20 K: 4 M: 1 F: 7 P: 6 S: 15 T: 5 W: 5 Y: 3 V: 13

Length

162

Formula

C798H1214N226O240S7

Mass

18038.21

PI

5.45

Net Charge

-7

Boman Index

26.41

Hydrophobicity

-0.229

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.