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Peptide record

TPDB16199

P3 Antibacterial Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB16199
P3
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
dbAMP CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from dbAMP, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
Sequence
RRRQKRIVVRRRLIR
Physicochemical Analysis
C87H169N41O17
ANDCEGHMFPSTWY
R
2061.56
13.25
9
0
5
+9
7.01
-1.480
116.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
2
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
15
C87H169N41O17
2061.56
13.25
+9
7.01
-1.480
Free
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

P. falciparum trophozoite stage cells
P. falciparum trophozoite stage cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
SYBR green-I, doxorubicin and actinomycin D
In vivo
CCCCCTTC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 And HeLa Cells , Staphylococcus Atcc 33591

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L Cationic
Synthetic
FITC labelled
Cytoplasm
P8–antibiotics combination was more effective
In vitro
CCCSSSTTCCCTTTTC
Additional Detail Fields 1 fields
CCCCCTTC CCCSSSTTCCCTTTTC