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Peptide record

TPDB16174

Anti-inflammatory Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB16174
Anti-inflammatory Antibacterial Antifungal Toxicity
Anti-infective peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia dbAMP AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 12-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, Antifungal, and other sources) peptide sequence curated from Peptipedia, dbAMP, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
AAVTRRILCWFA
Physicochemical Analysis
C65H103N19O14S1
NDEQGHKMPSY
A
1406.71
10.90
2
0
8
+2
-2.77
1.050
114.17
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
390.98
2
Residue Composition
number
3
A
2
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
12
C65H103N19O14S1
1406.71
10.90
+2
-2.77
1.050
Evidence Records 6 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 32 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 2 Activity

Activity

13% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
13% Hemolysis | 256 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 3 Activity

Activity

22% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
22% Hemolysis | 512 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 4 Activity

Activity

0% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 32 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 5 Activity

Activity

13% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
13% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 6 Activity

Activity

18% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 512 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021