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Peptide record

TPDB16108

Antibacterial Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB16108
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
VIHKWKLFKKIGAVLKVL
Physicochemical Analysis
C106H178N26O19
RNDCEQMPSTY
K
2120.74
11.12
6
0
11
+5
0.68
0.756
162.22
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
259.34
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
18
C106H178N26O19
2120.74
11.12
+5
0.68
0.756
Evidence Records 2 records
Evidence 1 Activity

Activity

29±3% Hemolysis
Toxicity
34 µM
Hemolytic Cytotoxic
29±3% Hemolysis | 34 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and Antibiofilm Activities of Helical Antimicrobial Peptide Sequences Incorporating Metal-Binding Motifs. | Biochemistry | 2019
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis