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Peptide record

TPDB16076

Antibacterial standard
190 amino acids
Basic Information
3D PDB MODEL
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TPDB16076
Antibacterial
Anti-infective peptides
dbAMP
standard
No
A 190-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.
Sequence
MTESLVLSPAPAKPKRVKASRRSASHPTYSEMIAAAIRAEKSRGGSSRQSIQKYIKSHYKVGHNADLQIKLSIRRLLAAGVLKQTKGVGASGSFRLAKSDKAKRSPGKKKKAVRRSTSPKKAARPRKARSPAKKPKATARKARKKSRASPKKAKKPKTVKAKSRKASKAKKVKRSKPRAKSGARKSPKKK
Physicochemical Analysis
C903H1599N311O241S2
CW
K
20733.69
12.59
69
5
57
+61
70.56
-1.151
56.21
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
4470
21.56
40
Residue Composition
number
29
A
22
R
1
N
2
D
0
C
3
E
4
Q
9
G
3
H
6
I
8
L
44
K
2
M
1
F
13
P
26
S
6
T
0
W
3
Y
8
V
Amino Acid Distribution
A: 29 R: 22 N: 1 D: 2 C: 0 E: 3 Q: 4 G: 9 H: 3 I: 6 L: 8 K: 44 M: 2 F: 1 P: 13 S: 26 T: 6 W: 0 Y: 3 V: 8
Chemical Descriptors
190
C903H1599N311O241S2
20733.69
12.59
+61
70.56
-1.151
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.8 µg/mL

Target

B. cereus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ B. cereus (MIC 3.8 ug/ml), E-faecalis (MIC >32 ug/ml), L. monocytogenes (MIC 4 ug/ml), S. aureus or MRSA (MIC 2.4-3
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

L. monocytogenes

Source & Reference

dbAMP

Other

Active against Gram+ B. cereus (MIC 3.8 ug/ml), E-faecalis (MIC >32 ug/ml), L. monocytogenes (MIC 4 ug/ml), S. aureus or MRSA (MIC 2.4-3.8 ug/ml), anti-VRE (MIC 4 ug/ml), Gram- E. coli (MIC 4.9 ug
Evidence 3 Activity

Activity

MIC
Antibacterial
2.4-3.8 µg/mL

Target

Staphylococcus aureus or MRSA

Source & Reference

dbAMP

Other

m+ B. cereus (MIC 3.8 ug/ml), E-faecalis (MIC >32 ug/ml), L. monocytogenes (MIC 4 ug/ml), S. aureus or MRSA (MIC 2.4-3.8 ug/ml), anti-VRE (MIC 4 ug/ml), Gram- E. coli (MIC 4.9 ug/ml), P. aeruginosa (MIC 2.9 ug/ml), an
Evidence 4 Activity

Activity

MIC
Antibacterial
4.9 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

genes (MIC 4 ug/ml), S. aureus or MRSA (MIC 2.4-3.8 ug/ml), anti-VRE (MIC 4 ug/ml), Gram- E. coli (MIC 4.9 ug/ml), P. aeruginosa (MIC 2.9 ug/ml), and S. typhimurium (MIC 1.9 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
2.9 µg/mL

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

ureus or MRSA (MIC 2.4-3.8 ug/ml), anti-VRE (MIC 4 ug/ml), Gram- E. coli (MIC 4.9 ug/ml), P. aeruginosa (MIC 2.9 ug/ml), and S. typhimurium (MIC 1.9 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
1.9 µg/mL

Target

S. typhimurium

Source & Reference

dbAMP

Other

anti-VRE (MIC 4 ug/ml), Gram- E. coli (MIC 4.9 ug/ml), P. aeruginosa (MIC 2.9 ug/ml), and S. typhimurium (MIC 1.9 ug/ml).