TPDB

3D PDB MODEL

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TPDB ID TPDB16063

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 204-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MSDTMVVNGSGGVPAFLFSGSTLSSYRPNFEANSITIALPHYVDLPGRSNFKLMYIMGFPIDTEMEKDSEYSNKIRQESKISKTEGTVSYEQKITVETGQEKDGVKVYRVMVLEGTIAESIEHLDKKENEDILNNNRNRIVLADNTVINFDNISQLKEFLRRSVGGGGSGGGGSGGGGSMMRVMRRKTKVIWEKKDFIGLYSID

FASTA

>TPDB16063|Antibacterial|length=204
MSDTMVVNGSGGVPAFLFSGSTLSSYRPNFEANSITIALPHYVDLPGRSNFKLMYIMGFPIDTEMEKDSEYSNKIRQESKISKTEGTVSYEQKITVETGQEKDGVKVYRVMVLEGTIAESIEHLDKKENEDILNNNRNRIVLADNTVINFDNISQLKEFLRRSVGGGGSGGGGSGGGGSMMRVMRRKTKVIWEKKDFIGLYSID

Formula C988H1580N274O314S9

Absent Amino Acids C

Common Amino Acids G

Mass 22609.60

PI 6.20

Basic Residues 28

Acidic Residues 27

Hydrophobic Residues 73

Net Charge -1

Boman Index 54.91

Hydrophobicity -0.442

Aliphatic Index 77.30

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 15930

Absorbance 280nm 70.46

Polar Residues 55

number

5

A

11

R

13

N

11

D

0

C

16

E

4

Q

23

G

2

H

16

I

12

L

15

K

9

M

8

F

5

P

20

S

11

T

1

W

7

Y

15

V

Amino Acid Distribution

A: 5 R: 11 N: 13 D: 11 C: 0 E: 16 Q: 4 G: 23 H: 2 I: 16 L: 12 K: 15 M: 9 F: 8 P: 5 S: 20 T: 11 W: 1 Y: 7 V: 15

Length

204

Formula

C988H1580N274O314S9

Mass

22609.60

PI

6.20

Net Charge

-1

Boman Index

54.91

Hydrophobicity

-0.442

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.