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Peptide record

TPDB16003

Antibacterial Antifungal Toxicity modified_plain modified
16 amino acids
Basic Information
3D PDB MODEL
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TPDB16003
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
modified_plain
Yes
A 16-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
XLFDVIKKVASVIGGL
Physicochemical Analysis
C74H127N17O19
RNCEQHMPTWY
V
1558.92
9.88
2
1
9
+1
0.53
1.306
158.12
Mammalian: Yeast: E.coli:
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
2
I
2
L
2
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
16
C74H127N17O19
1558.92
9.88
+1
0.53
1.306
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>32 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity. | Peptides | 2019
Evidence 2 Activity

Activity

IC50
Toxicity
19.14 µg/mL
Cytotoxic
IC50 | 19.14 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity. | Peptides | 2019