TPDB

3D PDB MODEL

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TPDB ID TPDB15932

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

modified_plain

Has_Modification Yes

Description A 121-aa modified antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Modification

Modified, details unspecified

Sequence

SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKXXXXXXXXXDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKXXXX

FASTA

>TPDB15932|Antibacterial|length=121
SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKXXXXXXXXXDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKXXXX

Formula C541H853N151O155S13

Absent Amino Acids

Common Amino Acids K

Mass 12369.42

PI 8.82

Basic Residues 23

Acidic Residues 11

Hydrophobic Residues 34

Net Charge +10

Boman Index 23.93

Hydrophobicity -0.594

Aliphatic Index 52.40

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 19660

Absorbance 280nm 158.94

Polar Residues 36

number

5

A

5

R

6

N

5

D

12

C

6

E

1

Q

9

G

2

H

3

I

9

L

16

K

1

M

2

F

4

P

4

S

4

T

1

W

9

Y

4

V

Amino Acid Distribution

A: 5 R: 5 N: 6 D: 5 C: 12 E: 6 Q: 1 G: 9 H: 2 I: 3 L: 9 K: 16 M: 1 F: 2 P: 4 S: 4 T: 4 W: 1 Y: 9 V: 4

Length

121

Formula

C541H853N151O155S13

Mass

12369.42

PI

8.82

Net Charge

+10

Boman Index

23.93

Hydrophobicity

-0.594

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.