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Peptide record

TPDB15825

Antibacterial Anticancer Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB15825
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Sequence
GRRPLLLRAR
Physicochemical Analysis
C52H98N22O11
NDCEQHIKMFSTWYV
R
1207.49
12.88
4
0
4
+4
1.85
-0.680
127.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
3
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C52H98N22O11
1207.49
12.88
+4
1.85
-0.680
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Antimicrobial Activity of Small Synthetic Peptides Based on the Marine Peptide Turgencin A: Prediction of Antimicrobial Peptide Sequences in a Natural Peptide and Strategy for Optimization of Potency. | Int J Mol Sci | 2020
Evidence 2 Activity

Activity

<1% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
<1% Hemolysis | 250 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity of Small Synthetic Peptides Based on the Marine Peptide Turgencin A: Prediction of Antimicrobial Peptide Sequences in a Natural Peptide and Strategy for Optimization of Potency. | Int J Mol Sci | 2020