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Peptide record

TPDB15821

Antibacterial Hemolysis Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB15821
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia PD_Hemolysis
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
CGCQLR
Physicochemical Analysis
C25H46N10O8S2
ANDEHIKMFPSTWYV
C
678.82
8.30
1
0
1
+1
0.36
0.067
65.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
18.41
3
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
0
E
1
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C25H46N10O8S2
678.82
8.30
+1
0.36
0.067
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Supramolecular amphipathicity for probing antimicrobial propensity of host defence peptides. | Phys Chem Chem Phys | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Supramolecular amphipathicity for probing antimicrobial propensity of host defence peptides. | Phys Chem Chem Phys | 2015
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis