Peptide record

TPDB15794

Antibacterial Anticancer Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15794
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Sequence
CASYFCRWWWLL
Physicochemical Analysis
C81H104N18O15S2
NDEQGHIKMPTV
W
1633.95
8.28
1
0
8
+1
-8.45
0.658
73.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
18115
1108.66
4
Residue Composition
number
1
A
1
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
1
F
0
P
1
S
0
T
3
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 3 Y: 1 V: 0
Chemical Descriptors
12
C81H104N18O15S2
1633.95
8.28
+1
-8.45
0.658
Evidence Records 2 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
4% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hybrid Antimicrobial Peptide Targeting Staphylococcus aureu s and Displaying Anti-infective Activity in a Murine Model. | Front Microbiol | 2020
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
1% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hybrid Antimicrobial Peptide Targeting Staphylococcus aureu s and Displaying Anti-infective Activity in a Murine Model. | Front Microbiol | 2020