Back to search

Peptide record

TPDB15785

Antibacterial Anticancer Antifungal Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB15785
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
HXLLPPVXPLFG
Physicochemical Analysis
C55H84N12O11
ARNDCEQIKMSTWY
LP
1089.35
7.85
1
0
5
+0
-0.42
0.833
121.67
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
3
L
0
K
0
M
1
F
3
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 3 K: 0 M: 0 F: 1 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C55H84N12O11
1089.35
7.85
+0
-0.42
0.833
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Toxicity
>100 µM
Cytotoxic
IC50 | >100 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Callyaerins from the Marine Sponge Callyspongia aerizusa: Cyclic Peptides with Antitubercular Activity. | J Nat Prod | 2015
Evidence 2 Activity

Activity

IC90
Toxicity
>100 µM
Cytotoxic
IC90 | >100 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Callyaerins from the Marine Sponge Callyspongia aerizusa: Cyclic Peptides with Antitubercular Activity. | J Nat Prod | 2015
Evidence 3 Activity

Activity

IC50
Toxicity
100 µM
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: MRC-5:IC50>100µM IC90>100µM

Target

erythrocytes

Source & Reference

NA
DRAMP
J Nat Prod. 2015 Aug 28 78(8):1910-25.