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Peptide record

TPDB15760

Antibacterial Antifungal Toxicity modified_plain modified
3 source-reported length (unverified)
Basic Information
TPDB15760
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
modified_plain
Yes
A modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide record curated from dbAMP, Peptipedia, and CAFPdb, without an available 3D structural model. Source-reported length: 3 (unverified).
Modified, details unspecified
Sequence
XRR

Source notation is retained verbatim; residue notation and chemical identity have not been independently validated. The displayed length is source-reported and unverified.

Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
3 source-reported length (unverified)
Evidence Records 15 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
39.72 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 39.72 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
116.28 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 116.28 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
70.11 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 70.11 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
37.54 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 37.54 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
207.62 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 207.62 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
42.04 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 42.04 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ultrashort Cationic Lipopeptides-Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis | Molecules | 2020
Evidence 8 Activity

Activity

50% Hemolysis
Toxicity
>512 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 9 Activity

Activity

IC50
Toxicity
32.12±6.26 µg/mL
Cytotoxic
IC50 | 32.12±6.26 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 10 Activity

Activity

IC50
Toxicity
10.61±2.04 µg/mL
Cytotoxic
IC50 | 10.61±2.04 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 11 Activity

Activity

50% Hemolysis
Toxicity
95.39±2.40 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 95.39±2.40 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 12 Activity

Activity

50% Hemolysis
Toxicity
77.45±1.13 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 77.45±1.13 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 13 Activity

Activity

IC50
Toxicity
10.12±0.66 µg/mL
Cytotoxic
IC50 | 10.12±0.66 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Glycosylated Lipopeptides-Synthesis and Evaluation of Antimicrobial Activity and Cytotoxicity | Biomolecules | 2023
Evidence 14 Activity

Activity

50% Hemolysis
Toxicity
110 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 110 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Discovery of novel histidine-derived lipo-amino acids: applied in the synthesis of ultra-short antimicrobial peptidomimetics having potent antimicrobial activity, salt resistance and protease stability | Eur J Med Chem | 2013
Evidence 15 Activity

Activity

10% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Non hemolytic short peptidomimetics as a new class of potent and broad-spectrum antimicrobial agents. | Bioorg Med Chem Lett | 2013