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Peptide record

TPDB15750

Antibacterial Anticancer Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB15750
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
XVTXVXVXXVXV
Physicochemical Analysis
C29H54N6O8
ARNDCEQGHILKMFPSWY
V
614.78
6.02
0
0
5
-0
0.49
1.692
120.83
Mammalian: Yeast: E.coli:
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 5
Chemical Descriptors
12
C29H54N6O8
614.78
6.02
-0
0.49
1.692
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Toxicity
>40 µM
Cytotoxic
IC50 | >40 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Ohmyungsamycins A and B: cytotoxic and antimicrobial cyclic peptides produced by Streptomyces sp. from a volcanic island. | J Org Chem | 2013
Evidence 2 Activity

Activity

50% Cell death
Toxicity
>40 µM
Cytotoxic
50% Cell death | >40 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Ohmyungsamycins A and B: cytotoxic and antimicrobial cyclic peptides produced by Streptomyces sp. from a volcanic island. | J Org Chem | 2013
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Org Chem. 2013 Dec 20 78(24):12321-9.