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Peptide record

TPDB15734

Antibacterial Anticancer Toxicity modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB15734
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia
modified_plain
Yes
A 17-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from dbAMP, DRAMP, and Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIKKFLKSXKKFVKXFK
Physicochemical Analysis
C91H152N22O17
ARNDCEQHMPTWY
K
1826.35
11.29
7
0
6
+7
2.88
-0.447
62.94
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
7
K
0
M
3
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 7 M: 0 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C91H152N22O17
1826.35
11.29
+7
2.88
-0.447
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
50% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence | ChemMedChem | 2019
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
50% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence | ChemMedChem | 2019
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.33466998] It has hemolysis against human red blood cells at 50 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Molecules. 2021 Jan 16 26(2):444. doi: 10.3390/molecules26020444.